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Structure paper

TitleStructural Insights into Ceftobiprole Inhibition of Pseudomonas aeruginosa Penicillin-Binding Protein 3.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 64, Year 2020
Publish dateJan 15, 2020 (structure data deposition date)
AuthorsKumar, V. / Tang, C. / Bethel, C.R. / Papp-Wallace, K.M. / Wyatt, J. / Desarbre, E. / Bonomo, R.A. / van den Akker, F.
External linksAntimicrob. Agents Chemother. / PubMed:32152075
MethodsX-ray diffraction
Resolution1.76 Å
Structure data

PDB-6vje:
Crystal structure of Pseudomonas aeruginosa penicillin-binding protein 3 (PBP3) complexed with ceftobiprole
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

Chemicals

ChemComp-RB6:
(2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / Antibiotic target / complex

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