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TitleMutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 4761-4772, Year 2020
Publish dateMar 4, 2019 (structure data deposition date)
AuthorsScaletti, E.R. / Vallin, K.S. / Brautigam, L. / Sarno, A. / Warpman Berglund, U. / Helleday, T. / Stenmark, P. / Jemth, A.S.
External linksJ. Biol. Chem. / PubMed:32144205
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-6qvo:
Crystal structure of human MTH1 in complex with N6-methyl-dAMP
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-6MA:
N6-METHYL-DEOXY-ADENOSINE-5'-MONOPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ----

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