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-Structure paper
Title | Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 3215-3226, Year 2020 |
Publish date | May 28, 2019 (structure data deposition date) |
Authors | Tanaka, Y. / Kurasawa, O. / Yokota, A. / Klein, M.G. / Ono, K. / Saito, B. / Matsumoto, S. / Okaniwa, M. / Ambrus-Aikelin, G. / Morishita, D. ...Tanaka, Y. / Kurasawa, O. / Yokota, A. / Klein, M.G. / Ono, K. / Saito, B. / Matsumoto, S. / Okaniwa, M. / Ambrus-Aikelin, G. / Morishita, D. / Kitazawa, S. / Uchiyama, N. / Ogawa, K. / Kimura, H. / Imamura, S. |
External links | J. Med. Chem. / PubMed:32142284 |
Methods | X-ray diffraction |
Resolution | 1.65 - 1.95 Å |
Structure data | PDB-6p4v: PDB-6pgr: |
Chemicals | ChemComp-NAD: ChemComp-GC7: ChemComp-MPD: ChemComp-HOH: ChemComp-8XY: |
Source |
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Keywords | TRANSFERASE/INHIBITOR / Deoxyhypusine / NAD cofactor / hypusine / spermidine / GC7 / transferase / TRANSFERASE-INHIBITOR complex / Inhibitor |