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TitlePDGFR-beta Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 142, Page 5204-5211, Year 2020
Publish dateNov 18, 2019 (structure data deposition date)
AuthorsWang, K.B. / Dickerhoff, J. / Wu, G. / Yang, D.
External linksJ. Am. Chem. Soc. / PubMed:32101424
MethodsNMR (solution)
Structure data

PDB-6v0l:
PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular Structure and Recognition of Guanine Derivatives and Metabolites
Method: SOLUTION NMR

Chemicals

ChemComp-DGP:
2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE

Source
  • homo sapiens (human)
KeywordsDNA / G-quadruplex / PDGFR-b / Promoter

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