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-Structure paper
Title | Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study. |
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Journal, issue, pages | Acs Chem. Biol., Year 2020 |
Publish date | Jan 8, 2015 (structure data deposition date) |
Authors | Bassenden, A.V. / Park, J. / Rodionov, D. / Berghuis, A.M. |
External links | Acs Chem. Biol. / PubMed:32100995 |
Methods | X-ray diffraction |
Resolution | 1.82 - 1.88 Å |
Structure data | PDB-4xje: PDB-5cfu: |
Chemicals | ChemComp-AMP: ChemComp-TOY: ChemComp-GOL: ChemComp-HOH: ChemComp-MN: ChemComp-51H: ChemComp-POP: ChemComp-BU1: |
Source |
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Keywords | transferase/antibiotic / antibiotic resistance / nucleotidyltransferase / tobramycin / Rossmann fold / transferase-antibiotic complex / AMPCPP / modified aminoglycoside |