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TitleStructural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376.
Journal, issue, pagesViruses, Vol. 12, Year 2020
Publish dateOct 30, 2019 (structure data deposition date)
AuthorsYe, G. / Wang, X. / Tong, X. / Shi, Y. / Fu, Z.F. / Peng, G.
External linksViruses / PubMed:32098094
MethodsX-ray diffraction
Resolution1.56 Å
Structure data

PDB-6l70:
Complex structure of PEDV 3CLpro with GC376
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-K36:
(1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid / medication, antivirus*YM

ChemComp-HOH:
WATER

Source
  • porcine epidemic diarrhea virus
KeywordsHYDROLASE / 3C-Like Protease / complex

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