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Structure paper

TitleStructures of human galectin-10/monosaccharide complexes demonstrate potential of monosaccharides as effectors in forming Charcot-Leyden crystals.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Year 2020
Publish dateOct 28, 2019 (structure data deposition date)
AuthorsItoh, A. / Nonaka, Y. / Nakakita, S.I. / Yoshida, H. / Nishi, N. / Nakamura, T. / Kamitori, S.
External linksBiochem. Biophys. Res. Commun. / PubMed:32081418
MethodsX-ray diffraction
Resolution1.77 - 2.08 Å
Structure data

PDB-6l64:
X-ray structure of human galectin-10 in complex with D-glucose
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-6l67:
X-ray structure of human galectin-10 in complex with D-galactose
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-6l68:
X-ray structure of human galectin-10 in complex with D-allose
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-6l6a:
X-ray structure of human galectin-10 in complex with D-mannose
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-6l6b:
X-ray structure of human galectin-10 in complex with L-fucose
Method: X-RAY DIFFRACTION / Resolution: 1.802 Å

PDB-6l6c:
X-ray structure of human galectin-10 in complex with D-arabinose
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

PDB-6l6d:
X-ray structure of human galectin-10 in complex with D-N-acetylgalactosamine
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-GAL:
beta-D-galactopyranose

ChemComp-ALL:
beta-D-allopyranose

ChemComp-BMA:
beta-D-mannopyranose

ChemComp-FUL:
beta-L-fucopyranose

ChemComp-64K:
alpha-D-arabinopyranose

ChemComp-NGA:
2-acetamido-2-deoxy-beta-D-galactopyranose

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / beta-sandwich structure / lectin

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