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TitleAn Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Journal, issue, pagesCell Host Microbe, Vol. 27, Page 428-440.e9, Year 2020
Publish dateApr 30, 2019 (structure data deposition date)
AuthorsKim, A.S. / Zimmerman, O. / Fox, J.M. / Nelson, C.A. / Basore, K. / Zhang, R. / Durnell, L. / Desai, C. / Bullock, C. / Deem, S.L. ...Kim, A.S. / Zimmerman, O. / Fox, J.M. / Nelson, C.A. / Basore, K. / Zhang, R. / Durnell, L. / Desai, C. / Bullock, C. / Deem, S.L. / Oppenheimer, J. / Shapiro, B. / Wang, T. / Cherry, S. / Coyne, C.B. / Handley, S.A. / Landis, M.J. / Fremont, D.H. / Diamond, M.S.
External linksCell Host Microbe / PubMed:32075743
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-6ort:
Crystal Structure of Bos taurus Mxra8 Ectodomain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsMEMBRANE PROTEIN / Receptor / Chikungunya virus / Cow / Bovine / Alphavirus / Moo insertion / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID

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