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TitleNovel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.
Journal, issue, pagesCancer Sci., Vol. 111, Page 1750-1760, Year 2020
Publish dateAug 28, 2019 (structure data deposition date)
AuthorsLiu, H. / Zheng, S. / Hou, X. / Liu, X. / Du, K. / Lv, X. / Li, Y. / Yang, F. / Li, W. / Sui, J.
External linksCancer Sci. / PubMed:32061104
MethodsX-ray diffraction
Resolution2.59775753879 Å
Structure data

PDB-6ktr:
Crystal structure of fibroblast growth factor 19 in complex with Fab
Method: X-RAY DIFFRACTION / Resolution: 2.59775753879 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/PROTEIN BINDING / complex / growth factor / antibody / CELL CYCLE / IMMUNE SYSTEM-PROTEIN BINDING complex

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