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TitleAllosteric Regulation of Hsp90 alpha's Activity by Small Molecules Targeting the Middle Domain of the Chaperone.
Journal, issue, pagesIscience, Vol. 23, Page 100857-100857, Year 2020
Publish dateAug 25, 2019 (structure data deposition date)
AuthorsZhou, C. / Zhang, C. / Zhu, H. / Liu, Z. / Su, H. / Zhang, X. / Chen, T. / Zhong, Y. / Hu, H. / Xiong, M. ...Zhou, C. / Zhang, C. / Zhu, H. / Liu, Z. / Su, H. / Zhang, X. / Chen, T. / Zhong, Y. / Hu, H. / Xiong, M. / Zhou, H. / Xu, Y. / Zhang, A. / Zhang, N.
External linksIscience / PubMed:32058968
MethodsX-ray diffraction
Resolution2.202 Å
Structure data

PDB-6ksq:
Middle Domain of Human HSP90 Alpha
Method: X-RAY DIFFRACTION / Resolution: 2.202 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCHAPERONE / HSP90

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