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TitleDefective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation inNeisseria meningitidis.
Journal, issue, pagesElife, Vol. 9, Year 2020
Publish dateJul 24, 2018 (structure data deposition date)
AuthorsWilliams, A.H. / Wheeler, R. / Deghmane, A.E. / Santecchia, I. / Schaub, R.E. / Hicham, S. / Moya Nilges, M. / Malosse, C. / Chamot-Rooke, J. / Haouz, A. ...Williams, A.H. / Wheeler, R. / Deghmane, A.E. / Santecchia, I. / Schaub, R.E. / Hicham, S. / Moya Nilges, M. / Malosse, C. / Chamot-Rooke, J. / Haouz, A. / Dillard, J.P. / Robins, W.P. / Taha, M.K. / Gomperts Boneca, I.
External linksElife / PubMed:32022687
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6h5f:
LtgA disordered Helix
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • neisseria meningitidis nm422 (bacteria)
KeywordsTRANSFERASE / Peptidoglycan / antibiotic resistance / enzyme hub

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