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| Title | A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy. |
|---|---|
| Journal, issue, pages | Nat. Biotechnol., Vol. 38, Page 426-432, Year 2020 |
| Publish date | Dec 5, 2018 (structure data deposition date) |
Authors | Giordano-Attianese, G. / Gainza, P. / Gray-Gaillard, E. / Cribioli, E. / Shui, S. / Kim, S. / Kwak, M.J. / Vollers, S. / Corria Osorio, A.J. / Reichenbach, P. ...Giordano-Attianese, G. / Gainza, P. / Gray-Gaillard, E. / Cribioli, E. / Shui, S. / Kim, S. / Kwak, M.J. / Vollers, S. / Corria Osorio, A.J. / Reichenbach, P. / Bonet, J. / Oh, B.H. / Irving, M. / Coukos, G. / Correia, B.E. |
External links | Nat. Biotechnol. / PubMed:32015549 |
| Methods | X-ray diffraction |
| Resolution | 2.5 Å |
| Structure data | ![]() PDB-6iwb: |
| Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
| Source |
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Keywords | APOPTOSIS |
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homo sapiens (human)
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