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TitleThe discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 2866-2884, Year 2020
Publish dateMar 15, 2019 (structure data deposition date)
AuthorsTetley, G.J.N. / Murphy, N.P. / Bonetto, S. / Ivanova-Berndt, G. / Revell, J. / Mott, H.R. / Cooley, R.N. / Owen, D.
External linksJ. Biol. Chem. / PubMed:31959628
MethodsNMR (solution)
Structure data

PDB-6r28:
Structure of peptide P7, which binds Cdc42 and inhibits effector interactions.
Method: SOLUTION NMR

Source
  • synthetic construct (others)
KeywordsDE NOVO PROTEIN / Inhibitor / cyclic peptide / synthetic peptide.

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