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Structure paper

TitleThe First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.
Journal, issue, pagesJ. Mol. Biol., Vol. 432, Page 1126-1142, Year 2020
Publish dateSep 4, 2019 (structure data deposition date)
AuthorsScaletti, E. / Claesson, M. / Helleday, T. / Jemth, A.S. / Stenmark, P.
External linksJ. Mol. Biol. / PubMed:31954130
MethodsX-ray diffraction
Resolution1.8 - 1.9 Å
Structure data

PDB-6sqw:
Mouse dCTPase in complex with 5-Me-dCMP
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6sqy:
Mouse dCTPase in complex with dCMP
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-6sqz:
Mouse dCTPase in complex with dCMPNPP
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-5CM:
5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-DCM:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE

ChemComp-0KX:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / 5-Me-dCMP complex / dCMP complex / dCMPNPP complex

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