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Structure paper

TitleA Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
Journal, issue, pagesJ. Mol. Biol., Vol. 432, Page 913-929, Year 2020
Publish dateJun 16, 2018 (structure data deposition date)
AuthorsVangaveti, S. / Cantara, W.A. / Spears, J.L. / DeMirci, H. / Murphy IV, F.V. / Ranganathan, S.V. / Sarachan, K.L. / Agris, P.F.
External linksJ. Mol. Biol. / PubMed:31945376
MethodsX-ray diffraction
Resolution3.33 - 3.54 Å
Structure data

PDB-6dti:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.54 Å

PDB-6mkn:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.46 Å

PDB-6mpf:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

PDB-6mpi:
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

Chemicals

ChemComp-PAR:
PAROMOMYCIN / Antimicrobial, medication*YM

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • thermus thermophilus hb8 (bacteria)
  • escherichia coli (E. coli)
  • thermus thermophilus hb8 (strain hb8 / atcc 27634 / dsm 579) (bacteria)
  • thermus thermophilus (strain hb8 / atcc 27634 / dsm 579) (bacteria)
KeywordsRIBOSOME / 2-thiocytidine / inosine / transfer RNA / tRNA / 30S / translation / anticodon

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