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-Structure paper
Title | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. |
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Journal, issue, pages | Cell Chem Biol, Vol. 27, Page 269-282.e5, Year 2020 |
Publish date | Aug 29, 2019 (structure data deposition date) |
Authors | Caplan, T. / Lorente-Macias, A. / Stogios, P.J. / Evdokimova, E. / Hyde, S. / Wellington, M.A. / Liston, S. / Iyer, K.R. / Puumala, E. / Shekhar-Guturja, T. ...Caplan, T. / Lorente-Macias, A. / Stogios, P.J. / Evdokimova, E. / Hyde, S. / Wellington, M.A. / Liston, S. / Iyer, K.R. / Puumala, E. / Shekhar-Guturja, T. / Robbins, N. / Savchenko, A. / Krysan, D.J. / Whitesell, L. / Zuercher, W.J. / Cowen, L.E. |
External links | Cell Chem Biol / PubMed:31924499 |
Methods | X-ray diffraction |
Resolution | 2.45 - 2.61 Å |
Structure data | PDB-6u69: PDB-6u6a: |
Chemicals | ChemComp-SO4: ChemComp-GOL: ChemComp-CL: ChemComp-HOH: ChemComp-Q0J: |
Source |
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Keywords | TRANSFERASE / casein kinase 1 / Yck2 / kinase / structural genomics / center for structural genomics of infectious diseases / niaid / national institute of allergy and infectious diseases / CSGID / TRANSFERASE/TRANSFERASE Inhibitor / kinase inhibitor / TRANSFERASE-TRANSFERASE Inhibitor complex |