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TitleHuman T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.
Journal, issue, pagesSci Immunol, Vol. 5, Year 2020
Publish dateFeb 3, 2019 (structure data deposition date)
AuthorsNicolai, S. / Wegrecki, M. / Cheng, T.Y. / Bourgeois, E.A. / Cotton, R.N. / Mayfield, J.A. / Monnot, G.C. / Le Nours, J. / Van Rhijn, I. / Rossjohn, J. ...Nicolai, S. / Wegrecki, M. / Cheng, T.Y. / Bourgeois, E.A. / Cotton, R.N. / Mayfield, J.A. / Monnot, G.C. / Le Nours, J. / Van Rhijn, I. / Rossjohn, J. / Moody, D.B. / de Jong, A.
External linksSci Immunol / PubMed:31901073
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-6nux:
CD1a-lipid binary complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-FOF:
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / contact hypersensitivity / antigen presentation / HLA class I-like

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