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-Structure paper
Title | X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance. |
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Journal, issue, pages | Biochemistry, Vol. 59, Page 627-634, Year 2020 |
Publish date | Feb 4, 2019 (structure data deposition date) |
![]() | Thomaston, J.L. / Konstantinidi, A. / Liu, L. / Lambrinidis, G. / Tan, J. / Caffrey, M. / Wang, J. / Degrado, W.F. / Kolocouris, A. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 3.01 Å |
Structure data | ![]() PDB-6nv1: ![]() PDB-6oug: |
Chemicals | ![]() ChemComp-OLC: ![]() ChemComp-E01: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | MEMBRANE PROTEIN / proton channel / viral protein |