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Structure paper

TitleDesign and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models.
Journal, issue, pagesMabs, Vol. 12, Page 1685350-1685350, Year 2019
Publish dateOct 18, 2019 (structure data deposition date)
AuthorsWang, F. / Tsai, J.C. / Davis, J.H. / Chau, B. / Dong, J. / West, S.M. / Hogan, J.M. / Wheeler, M.L. / Bee, C. / Morishige, W. ...Wang, F. / Tsai, J.C. / Davis, J.H. / Chau, B. / Dong, J. / West, S.M. / Hogan, J.M. / Wheeler, M.L. / Bee, C. / Morishige, W. / Cayton, T. / David-Brown, D. / Zhang, C. / Kozhich, A. / Sproul, T. / Dollinger, G. / Rajpal, A. / Strop, P.
External linksMabs / PubMed:31856660
MethodsX-ray diffraction
Resolution1.87 Å
Structure data

PDB-6uqc:
Mouse IgG2a Bispecific Fc
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Bispecific / Electrostatic Steering / Fc

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