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Structure paper

TitlePARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Journal, issue, pagesNat Commun, Vol. 10, Page 5751-5751, Year 2019
Publish dateNov 4, 2018 (structure data deposition date)
AuthorsSharma, D. / De Falco, L. / Padavattan, S. / Rao, C. / Geifman-Shochat, S. / Liu, C.F. / Davey, C.A.
External linksNat Commun / PubMed:31848352
MethodsX-ray diffraction
Resolution1.99 - 2.85 Å
Structure data

PDB-6ipu:
Human nucleosome core particle containing 145 bp of DNA
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-6jxd:
Human nucleosome core particle with cohesive end DNA termini
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-6k1i:
Human nucleosome core particle with gammaH2A.X variant
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-6k1j:
Human nucleosome core particle with H2A.X variant
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-6k1k:
Human nucleosome core particle with H2A.X S139E variant
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN/DNA / Nucleosome / DNA BINDING PROTEIN-DNA complex / DNA BINDING PROTEIN / gammaH2A.X / H2A.X

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