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TitleCooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycans.
Journal, issue, pagesPlos Pathog., Vol. 15, Page e1008165-e1008165, Year 2019
Publish dateMay 23, 2019 (structure data deposition date)
AuthorsWu, N.R. / Nicely, N.I. / Lee, E.M. / Reed, R.K. / Watts, B.E. / Cai, F. / Walkowicz, W.E. / Aussedat, B. / Jones, J.A. / Eaton, A. ...Wu, N.R. / Nicely, N.I. / Lee, E.M. / Reed, R.K. / Watts, B.E. / Cai, F. / Walkowicz, W.E. / Aussedat, B. / Jones, J.A. / Eaton, A. / Trama, A.M. / Alam, S.M. / Montefiori, D.C. / Haynes, B.F. / Saunders, K.O.
External linksPlos Pathog. / PubMed:31841553
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-6p3b:
Crystal structure of the anti-HIV antibody DH501 unmutated common ancestor (UCA)
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • macaca mulatta (Rhesus monkey)
KeywordsIMMUNE SYSTEM / HIV

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