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TitleMapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth.
Journal, issue, pagesJ. Virol., Vol. 94, Year 2020
Publish dateJun 19, 2019 (structure data deposition date)
AuthorsQiu, Y. / Stegalkina, S. / Zhang, J. / Boudanova, E. / Park, A. / Zhou, Y. / Prabakaran, P. / Pougatcheva, S. / Ustyugova, I.V. / Vogel, T.U. ...Qiu, Y. / Stegalkina, S. / Zhang, J. / Boudanova, E. / Park, A. / Zhou, Y. / Prabakaran, P. / Pougatcheva, S. / Ustyugova, I.V. / Vogel, T.U. / Mundle, S.T. / Oomen, R. / Delagrave, S. / Ross, T.M. / Kleanthous, H. / Qiu, H.
External linksJ. Virol. / PubMed:31826999
MethodsX-ray diffraction
Resolution3.993 Å
Structure data

PDB-6pdx:
Crystal structure of C585 Fab in complex with influenza virus hemagglutinin from A/Switzerland/9715293/2013 (H3N2)
Method: X-RAY DIFFRACTION / Resolution: 3.993 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • influenza a virus
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Influenza virus / Hemagglutinin / broadly neutralizing antibody / H3N2 / VIRAL PROTEIN

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