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Structure paper

TitleFunctions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.
Journal, issue, pagesMutagenesis, Vol. 35, Page 27-38, Year 2020
Publish dateJun 9, 2019 (structure data deposition date)
AuthorsMcNeill, D.R. / Whitaker, A.M. / Stark, W.J. / Illuzzi, J.L. / McKinnon, P.J. / Freudenthal, B.D. / Wilson, D.M.
External linksMutagenesis / PubMed:31816044
MethodsX-ray diffraction
Resolution2.09 - 2.1 Å
Structure data

PDB-6p93:
Human APE1 K98A AP-endonuclease product complex
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6p94:
Human APE1 C65A AP-endonuclease product complex
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsLYASE/DNA / APE1 / nuclease / dna repair / DNA BINDING PROTEIN / LYASE-DNA complex

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