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Structure paper

TitleA Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase.
Journal, issue, pagesBiochemistry, Vol. 58, Page 5160-5172, Year 2019
Publish dateOct 11, 2019 (structure data deposition date)
AuthorsAoto, P.C. / Stanfield, R.L. / Wilson, I.A. / Dyson, H.J. / Wright, P.E.
External linksBiochemistry / PubMed:31794659
MethodsX-ray diffraction
Resolution2.554 Å
Structure data

PDB-6una:
Crystal structure of inactive p38gamma
Method: X-RAY DIFFRACTION / Resolution: 2.554 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / MAPK / mitogen activated protein kinase / p38 gamma / MAPK12 / inactive kinase

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