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TitleStructural Mechanism of Regioselectivity in an Unusual Bacterial Acyl-CoA Dehydrogenase.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 142, Page 835-846, Year 2020
Publish dateAug 16, 2019 (structure data deposition date)
AuthorsBlake-Hedges, J.M. / Pereira, J.H. / Cruz-Morales, P. / Thompson, M.G. / Barajas, J.F. / Chen, J. / Krishna, R.N. / Chan, L.J.G. / Nimlos, D. / Alonso-Martinez, C. ...Blake-Hedges, J.M. / Pereira, J.H. / Cruz-Morales, P. / Thompson, M.G. / Barajas, J.F. / Chen, J. / Krishna, R.N. / Chan, L.J.G. / Nimlos, D. / Alonso-Martinez, C. / Baidoo, E.E.K. / Chen, Y. / Gin, J.W. / Katz, L. / Petzold, C.J. / Adams, P.D. / Keasling, J.D.
External linksJ. Am. Chem. Soc. / PubMed:31793780
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-6u1v:
Crystal structure of acyl-ACP/acyl-CoA dehydrogenase from allylmalonyl-CoA and FK506 biosynthesis, TcsD
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-FDA:
DIHYDROFLAVINE-ADENINE DINUCLEOTIDE

ChemComp-HOH:
WATER

Source
  • streptomyces tsukubensis (strain dsm 42081 / nbrc 108919 / nrrl 18488 / 9993) (bacteria)
KeywordsOXIDOREDUCTASE / ACAD / FK506 / allylmalonyl-CoA

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