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Structure paper

TitleMechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin.
Journal, issue, pagesNat Commun, Vol. 10, Page 5320-5320, Year 2019
Publish dateMay 22, 2019 (structure data deposition date)
AuthorsKotila, T. / Wioland, H. / Enkavi, G. / Kogan, K. / Vattulainen, I. / Jegou, A. / Romet-Lemonne, G. / Lappalainen, P.
External linksNat Commun / PubMed:31757941
MethodsX-ray diffraction
Resolution1.95 - 2.37 Å
Structure data

PDB-6rsq:
Helical folded domain of mouse CAP1
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

PDB-6rsw:
HFD domain of mouse CAP1 bound to the pointed end of G-actin
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

Source
  • mus musculus (house mouse)
  • oryctolagus cuniculus (rabbit)
KeywordsCONTRACTILE PROTEIN / Actin binding protein

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