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TitleCrystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateNov 8, 2018 (structure data deposition date)
AuthorsZhou, Y. / Cao, C. / He, L. / Wang, X. / Zhang, X.C.
External linksElife / PubMed:31750832
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-6iql:
Crystal structure of dopamine receptor D4 bound to the subtype-selective ligand, L745870
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-L74:
3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-1H-pyrrolo[2,3-b]pyridine / antipsychotic, antagonist*YM

Source
  • mus musculus (house mouse)
  • escherichia coli (E. coli)
KeywordsSIGNALING PROTEIN / GPCR / DRD4 / L745870 / ligand / dimerization

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