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Structure paper

TitleAtomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
Journal, issue, pagesJ. Gen. Physiol., Vol. 152, Year 2020
Publish dateAug 21, 2018 (structure data deposition date)
AuthorsZangerl-Plessl, E.M. / Lee, S.J. / Maksaev, G. / Bernsteiner, H. / Ren, F. / Yuan, P. / Stary-Weinzinger, A. / Nichols, C.G.
External linksJ. Gen. Physiol. / PubMed:31744859
MethodsX-ray diffraction
Resolution2.71 - 2.81 Å
Structure data

PDB-6m84:
Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

PDB-6m85:
Crystal Structure of Inward Rectifier Kir2.2 in a different salt condition
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-PIO:
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

ChemComp-LMT:
DODECYL-BETA-D-MALTOSIDE / detergent*YM

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsMETAL TRANSPORT / Kir 2.2 force open mutant / complex / Kir 2.2

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