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TitleA Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Journal, issue, pagesCancer Res., Vol. 80, Page 536-548, Year 2020
Publish dateDec 17, 2019 (structure data deposition date)
AuthorsWang, Y. / Huang, J. / Li, B. / Xue, H. / Tricot, G. / Hu, L. / Xu, Z. / Sun, X. / Chang, S. / Gao, L. ...Wang, Y. / Huang, J. / Li, B. / Xue, H. / Tricot, G. / Hu, L. / Xu, Z. / Sun, X. / Chang, S. / Gao, L. / Tao, Y. / Xu, H. / Xie, Y. / Xiao, W. / Yu, D. / Kong, Y. / Chen, G. / Lian, F. / Zhang, N. / Wu, X. / Mao, Z. / Zhan, F. / Zhu, W. / Shi, J.
External linksCancer Res. / PubMed:31732653
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-6lk0:
Crystal structure of human wild type TRIP13
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN / AAA+ ATPase / hexamer helical filament / ATP-bound / conformation dynamic

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