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TitleBypass of the Major Alkylative DNA Lesion by Human DNA Polymerase eta.
Journal, issue, pagesMolecules, Vol. 24, Year 2019
Publish dateSep 30, 2019 (structure data deposition date)
AuthorsKoag, M.C. / Jung, H. / Kou, Y. / Lee, S.
External linksMolecules / PubMed:31683505
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-6ui2:
Structure of human DNA polymerase eta complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-0KX:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN/DNA / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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