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TitleCapturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Journal, issue, pagesStructure, Vol. 27, Page 1771-, Year 2019
Publish dateJul 22, 2019 (structure data deposition date)
AuthorsCassidy, K.C. / Lahr, R.M. / Kaminsky, J.C. / Mack, S. / Fonseca, B.D. / Das, S.R. / Berman, A.J. / Durrant, J.D.
External linksStructure / PubMed:31676287
MethodsX-ray diffraction
Resolution2.34 Å
Structure data

PDB-6pw3:
LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / HEAT-like / cap-binding / TOP mRNA / translation regulation

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