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Structure paper

TitleStructure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 521, Page 31-36, Year 2020
Publish dateSep 3, 2019 (structure data deposition date)
AuthorsSun, H. / Ko, T.P. / Liu, W. / Zheng, Y. / Chen, C.C. / Guo, R.T.
External linksBiochem. Biophys. Res. Commun. / PubMed:31653344
MethodsX-ray diffraction
Resolution1.48 - 1.66 Å
Structure data

PDB-6kv9:
MoeE5 in complex with UDP-glucuronic acid and NAD
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

PDB-6kvc:
MoeE5 in complex with UDP-glucose and NAD
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-UGA:
URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID

ChemComp-HOH:
WATER

ChemComp-UPG:
URIDINE-5'-DIPHOSPHATE-GLUCOSE

Source
  • streptomyces viridosporus atcc 14672 (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / substrate / complex / antibiotic / epimerase / galacturonic acid

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