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Title | Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 9680-9690, Year 2019 |
Publish date | Jul 2, 2019 (structure data deposition date) |
Authors | McGowan, D.C. / Balemans, W. / Embrechts, W. / Motte, M. / Keown, J.R. / Buyck, C. / Corbera, J. / Funes, M. / Moreno, L. / Cooymans, L. ...McGowan, D.C. / Balemans, W. / Embrechts, W. / Motte, M. / Keown, J.R. / Buyck, C. / Corbera, J. / Funes, M. / Moreno, L. / Cooymans, L. / Tahri, A. / Eymard, J. / Stoops, B. / Strijbos, R. / Van den Berg, J. / Fodor, E. / Grimes, J.M. / Koul, A. / Jonckers, T.H.M. / Raboisson, P. / Guillemont, J. |
External links | J. Med. Chem. / PubMed:31647875 |
Methods | X-ray diffraction |
Resolution | 1.35 Å |
Structure data | PDB-6s5v: |
Chemicals | ChemComp-KWN: ChemComp-GOL: ChemComp-K: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN / Influenza A / H5N1 / Influenza polymerase / Cap binding analogue |