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Structure paper

TitleMolecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27.
Journal, issue, pagesMbio, Vol. 10, Year 2019
Publish dateDec 15, 2017 (structure data deposition date)
AuthorsTunnicliffe, R.B. / Hu, W.K. / Wu, M.Y. / Levy, C. / Mould, A.P. / McKenzie, E.A. / Sandri-Goldin, R.M. / Golovanov, A.P.
External linksMbio / PubMed:31641093
MethodsX-ray diffraction
Resolution2.801 Å
Structure data

PDB-6fad:
SR protein kinase 1 (SRPK1) in complex with the RGG-box of HSV1 ICP27
Method: X-RAY DIFFRACTION / Resolution: 2.801 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • herpes simplex virus (type 1 / strain 17)
KeywordsSPLICING / Complex / Phosphorylation / Inhibition

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