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TitleCharacterization of resistance to a potent D-peptide HIV entry inhibitor.
Journal, issue, pagesRetrovirology, Vol. 16, Page 28-28, Year 2019
Publish dateJul 12, 2019 (structure data deposition date)
AuthorsSmith, A.R. / Weinstock, M.T. / Siglin, A.E. / Whitby, F.G. / Francis, J.N. / Hill, C.P. / Eckert, D.M. / Root, M.J. / Kay, M.S.
External linksRetrovirology / PubMed:31640718
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-6psa:
PIE12 D-PEPTIDE AGAINST HIV ENTRY (IN COMPLEX WITH IQN17 Q577R RESISTANCE MUTANT)
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
  • saccharomyces cerevisiae (brewer's yeast)
  • human immunodeficiency virus type 1
KeywordsVIRAL PROTEIN/INHIBITOR / HIV / HELIX / HIV ENTRY INHIBITOR / IQN17 PIE12 / D-PEPTIDE INHIBITOR / VIRAL PROTEIN-INHIBITOR complex

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