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TitleStructure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions.
Journal, issue, pagesPharmaceutics, Vol. 11, Year 2019
Publish dateJun 3, 2019 (structure data deposition date)
AuthorsGallagher, D.T. / McCullough, C. / Brinson, R.G. / Ahn, J. / Marino, J.P. / Dimasi, N.
External linksPharmaceutics / PubMed:31640157
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-6p6d:
HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-CYS:
CYSTEINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody-drug conjugate / cysteine insertion mutant / cysteine disulfide adduct

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