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Structure paper

TitleControl of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Journal, issue, pagesNat. Immunol., Vol. 20, Page 1644-1655, Year 2019
Publish dateApr 6, 2018 (structure data deposition date)
AuthorsMelum, E. / Jiang, X. / Baker, K.D. / Macedo, M.F. / Fritsch, J. / Dowds, C.M. / Wang, J. / Pharo, A. / Kaser, A. / Tan, C. ...Melum, E. / Jiang, X. / Baker, K.D. / Macedo, M.F. / Fritsch, J. / Dowds, C.M. / Wang, J. / Pharo, A. / Kaser, A. / Tan, C. / Pereira, C.S. / Kelly, S.L. / Duan, J. / Karlsen, T.H. / Exley, M.A. / Schutze, S. / Zajonc, D.M. / Merrill, A.H. / Schuchman, E.H. / Zeissig, S. / Blumberg, R.S.
External linksNat. Immunol. / PubMed:31636468
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-6cyw:
Structure of sphingomyelin in complex with mouse CD1d
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-FO4:
sphingomyelin

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Glycolipid-antigen presentation / MHC-fold / Ig-fold

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