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TitleHuman leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 20246-20258, Year 2019
Publish dateAug 13, 2018 (structure data deposition date)
AuthorsMacLachlan, B.J. / Dolton, G. / Papakyriakou, A. / Greenshields-Watson, A. / Mason, G.H. / Schauenburg, A. / Besneux, M. / Szomolay, B. / Elliott, T. / Sewell, A.K. ...MacLachlan, B.J. / Dolton, G. / Papakyriakou, A. / Greenshields-Watson, A. / Mason, G.H. / Schauenburg, A. / Besneux, M. / Szomolay, B. / Elliott, T. / Sewell, A.K. / Gallimore, A. / Rizkallah, P. / Cole, D.K. / Godkin, A.
External linksJ. Biol. Chem. / PubMed:31619516
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-6hby:
HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HLA Class II / MHC II / Human / 5T4 tumor epitope

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