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-Structure paper
Title | Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 9045-9060, Year 2019 |
Publish date | Oct 24, 2018 (structure data deposition date) |
![]() | Bach, J. / Eastwood, P. / Gonzalez, J. / Gomez, E. / Alonso, J.A. / Fonquerna, S. / Lozoya, E. / Orellana, A. / Maldonado, M. / Calaf, E. ...Bach, J. / Eastwood, P. / Gonzalez, J. / Gomez, E. / Alonso, J.A. / Fonquerna, S. / Lozoya, E. / Orellana, A. / Maldonado, M. / Calaf, E. / Alberti, J. / Perez, J. / Andres, A. / Prats, N. / Carreno, C. / Calama, E. / De Alba, J. / Calbet, M. / Miralpeix, M. / Ramis, I. |
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Methods | X-ray diffraction |
Resolution | 2.2 - 2.46 Å |
Structure data | ![]() PDB-6hzu: ![]() PDB-6hzv: |
Chemicals | ![]() ChemComp-GYQ: ![]() ChemComp-HOH: ![]() ChemComp-GYW: |
Source |
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