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TitleStabilization of backbone-circularized protein is attained by synergistic gains in enthalpy of folded structure and entropy of unfolded structure.
Journal, issue, pagesFebs J., Year 2019
Publish dateApr 12, 2018 (structure data deposition date)
AuthorsShibuya, R. / Miyafusa, T. / Honda, S.
External linksFebs J. / PubMed:31605655
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5zo6:
Crystal structure of C166, a backbone circularized G-CSF
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / four-helix bundle / back-bone circularization

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