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TitleAgrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 116, Page 22331-22340, Year 2019
Publish dateApr 27, 2019 (structure data deposition date)
AuthorsWang, C. / Ye, F. / Chang, C. / Liu, X. / Wang, J. / Yan, X.F. / Fu, Q. / Zhou, J. / Chen, S. / Gao, Y.G. / Zhang, L.H.
External linksProc. Natl. Acad. Sci. USA / PubMed:31604827
MethodsX-ray diffraction
Resolution1.804 - 2.112 Å
Structure data

PDB-6rjk:
Structure of virulence factor SghA from Agrobacterium tumefaciens
Method: X-RAY DIFFRACTION / Resolution: 1.922 Å

PDB-6rjm:
Complex structure of virulence factor SghA and its hydrolysis product glucose
Method: X-RAY DIFFRACTION / Resolution: 2.112 Å

PDB-6rjo:
Complex structure of virulence factor SghA with its substrate analog salicin
Method: X-RAY DIFFRACTION / Resolution: 1.804 Å

PDB-6rk2:
Complex structure of virulence factor SghA mutant with its substrate SAG
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-SA0:
2-(hydroxymethyl)phenyl beta-D-glucopyranoside

ChemComp-6GR:
2-(alpha-L-altropyranosyloxy)benzoic acid

Source
  • agrobacterium tumefaciens a6 (bacteria)
KeywordsHYDROLASE / Chemical signaling / Sucrose / Agrobacterium / Host-pathogen interaction / Glucosidase

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