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TitleDinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Journal, issue, pagesMol. Cell, Vol. 76, Page 784-796.e6, Year 2019
Publish dateApr 11, 2019 (structure data deposition date)
AuthorsNicholls, T.J. / Spahr, H. / Jiang, S. / Siira, S.J. / Koolmeister, C. / Sharma, S. / Kauppila, J.H.K. / Jiang, M. / Kaever, V. / Rackham, O. ...Nicholls, T.J. / Spahr, H. / Jiang, S. / Siira, S.J. / Koolmeister, C. / Sharma, S. / Kauppila, J.H.K. / Jiang, M. / Kaever, V. / Rackham, O. / Chabes, A. / Falkenberg, M. / Filipovska, A. / Larsson, N.G. / Gustafsson, C.M.
External linksMol. Cell / PubMed:31588022
MethodsX-ray diffraction
Resolution1.97 - 2.25 Å
Structure data

PDB-6rci:
Crystal structure of REXO2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6rcl:
Crystal structure of REXO2-D199A-AA
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-6rcn:
Crystal structure of REXO2-D199A-dAdA
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE / Mitochondria / Oligoribonuclease / REXO2

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