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TitleIsolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Journal, issue, pagesImmunity, Vol. 51, Page 724-, Year 2019
Publish dateAug 8, 2019 (structure data deposition date)
AuthorsGorman, J. / Mason, R.D. / Nettey, L. / Cavett, N. / Chuang, G.Y. / Peng, D. / Tsybovsky, Y. / Verardi, R. / Nguyen, R. / Ambrozak, D. ...Gorman, J. / Mason, R.D. / Nettey, L. / Cavett, N. / Chuang, G.Y. / Peng, D. / Tsybovsky, Y. / Verardi, R. / Nguyen, R. / Ambrozak, D. / Biris, K. / LaBranche, C.C. / Ramesh, A. / Schramm, C.A. / Zhou, J. / Bailer, R.T. / Kepler, T.B. / Montefiori, D.C. / Shapiro, L. / Douek, D.C. / Mascola, J.R. / Roederer, M. / Kwong, P.D.
External linksImmunity / PubMed:31586542
MethodsX-ray diffraction
Resolution2.301 Å
Structure data

PDB-6tyb:
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • simian immunodeficiency virus
  • macaca mulatta (Rhesus monkey)
KeywordsIMMUNE SYSTEM / bNABs / gp120 / fab / glycan

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