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TitleS-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 58, Page 17583-17588, Year 2019
Publish dateJun 12, 2019 (structure data deposition date)
AuthorsMcKean, I.J.W. / Sadler, J.C. / Cuetos, A. / Frese, A. / Humphreys, L.D. / Grogan, G. / Hoskisson, P.A. / Burley, G.A.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:31573135
MethodsX-ray diffraction
Resolution1.5 - 1.77 Å
Structure data

PDB-6ryz:
SalL with S-adenosyl methionine
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-6rz2:
SalL with Chloroadenosine
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-5CD:
5'-CHLORO-5'-DEOXYADENOSINE

Source
  • salinispora tropica cnb-440 (bacteria)
KeywordsTRANSFERASE / SalL / S-adenosyl methionine / chlorinase / chloroadenosine

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