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Structure paper

TitlePromutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
Journal, issue, pagesMolecules, Vol. 24, Year 2019
Publish dateMar 17, 2018 (structure data deposition date)
AuthorsKou, Y. / Koag, M.C. / Lee, S.
External linksMolecules / PubMed:31569643
MethodsX-ray diffraction
Resolution2.327 Å
Structure data

PDB-6crh:
Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP
Method: X-RAY DIFFRACTION / Resolution: 2.327 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-XG4:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase / Lyase/DNA / DNA binding Protein / Lyase-DNA complex

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