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TitleMutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 17371-17382, Year 2019
Publish dateMay 31, 2019 (structure data deposition date)
AuthorsMachackova, K. / Mlcochova, K. / Potalitsyn, P. / Hankova, K. / Socha, O. / Budesinsky, M. / Muzdalo, A. / Lepsik, M. / Cernekova, M. / Radosavljevic, J. ...Machackova, K. / Mlcochova, K. / Potalitsyn, P. / Hankova, K. / Socha, O. / Budesinsky, M. / Muzdalo, A. / Lepsik, M. / Cernekova, M. / Radosavljevic, J. / Fabry, M. / Mitrova, K. / Chrudinova, M. / Lin, J. / Yurenko, Y. / Hobza, P. / Selicharova, I. / Zakova, L. / Jiracek, J.
External linksJ. Biol. Chem. / PubMed:31558604
MethodsNMR (solution)
Structure data

PDB-6rva:
STRUCTURE OF [ASP58]-IGF-I ANALOGUE
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsHORMONE / IGF-I ANALOGUE

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