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TitleA Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
Journal, issue, pagesJ Immunol., Vol. 203, Page 2545-2556, Year 2019
Publish dateMay 14, 2019 (structure data deposition date)
AuthorsGlesner, J. / Kapingidza, A.B. / Godzwon, M. / Offermann, L.R. / Mueller, G.A. / DeRose, E.F. / Wright, P. / Richardson, C.M. / Woodfolk, J.A. / Vailes, L.D. ...Glesner, J. / Kapingidza, A.B. / Godzwon, M. / Offermann, L.R. / Mueller, G.A. / DeRose, E.F. / Wright, P. / Richardson, C.M. / Woodfolk, J.A. / Vailes, L.D. / Wunschmann, S. / London, R.E. / Chapman, M.D. / Ohlin, M. / Chruszcz, M. / Pomes, A.
External linksJ Immunol. / PubMed:31554696
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-6oy4:
Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • dermatophagoides pteronyssinus (European house dust mite)
  • mus musculus (house mouse)
Keywordsallergen/immune system / Allergen / dust mite / antibody binding / allergen-immune system complex

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