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TitleDominant mutations in mtDNA maintenance gene SSBP1 cause optic atrophy and foveopathy.
Journal, issue, pagesJ. Clin. Invest., Vol. 130, Page 143-156, Year 2020
Publish dateMay 28, 2019 (structure data deposition date)
AuthorsPiro-Megy, C. / Sarzi, E. / Tarres-Sole, A. / Pequignot, M. / Hensen, F. / Quiles, M. / Manes, G. / Chakraborty, A. / Senechal, A. / Bocquet, B. ...Piro-Megy, C. / Sarzi, E. / Tarres-Sole, A. / Pequignot, M. / Hensen, F. / Quiles, M. / Manes, G. / Chakraborty, A. / Senechal, A. / Bocquet, B. / Cazevieille, C. / Roubertie, A. / Muller, A. / Charif, M. / Goudenege, D. / Lenaers, G. / Wilhelm, H. / Kellner, U. / Weisschuh, N. / Wissinger, B. / Zanlonghi, X. / Hamel, C. / Spelbrink, J.N. / Sola, M. / Delettre, C.
External linksJ. Clin. Invest. / PubMed:31550237
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6rup:
Human mitochondrial single-stranded DNA binding protein, SSBP1, at 2.1 A resolution - elucidated sequence
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Single-stranded DNA binding protein / mitochondria / mtDNA / mtDNA replication / mitochondrial RNA granules

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