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-Structure paper
Title | A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 9008-9025, Year 2019 |
Publish date | Nov 19, 2018 (structure data deposition date) |
Authors | Fagan, V. / Johansson, C. / Gileadi, C. / Monteiro, O. / Dunford, J.E. / Nibhani, R. / Philpott, M. / Malzahn, J. / Wells, G. / Faram, R. ...Fagan, V. / Johansson, C. / Gileadi, C. / Monteiro, O. / Dunford, J.E. / Nibhani, R. / Philpott, M. / Malzahn, J. / Wells, G. / Faram, R. / Cribbs, A.P. / Halidi, N. / Li, F. / Chau, I. / Greschik, H. / Velupillai, S. / Allali-Hassani, A. / Bennett, J. / Christott, T. / Giroud, C. / Lewis, A.M. / Huber, K.V.M. / Athanasou, N. / Bountra, C. / Jung, M. / Schule, R. / Vedadi, M. / Arrowsmith, C. / Xiong, Y. / Jin, J. / Fedorov, O. / Farnie, G. / Brennan, P.E. / Oppermann, U. |
External links | J. Med. Chem. / PubMed:31550156 |
Methods | X-ray diffraction |
Resolution | 1.52 - 1.76 Å |
Structure data | PDB-6i8b: PDB-6i8l: PDB-6i8y: |
Chemicals | ChemComp-H7T: ChemComp-DMS: ChemComp-GLY: ChemComp-PO4: ChemComp-HOH: ChemComp-MPD: ChemComp-MRD: ChemComp-H7Q: ChemComp-CL: ChemComp-2OD: ChemComp-EDO: ChemComp-GOL: ChemComp-NA: |
Source |
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Keywords | CELL CYCLE / Epigenetics / Tudor domain / Methyl-Lysine / methyl-Arginine / GENE REGULATION |