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-Structure paper
Title | Structural and Molecular Insight into Resistance Mechanisms of First Generation cMET Inhibitors. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 10, Page 1322-1327, Year 2019 |
Publish date | Jul 26, 2019 (structure data deposition date) |
Authors | Collie, G.W. / Koh, C.M. / O'Neill, D.J. / Stubbs, C.J. / Khurana, P. / Eddershaw, A. / Snijder, A. / Mauritzson, F. / Barlind, L. / Dale, I.L. ...Collie, G.W. / Koh, C.M. / O'Neill, D.J. / Stubbs, C.J. / Khurana, P. / Eddershaw, A. / Snijder, A. / Mauritzson, F. / Barlind, L. / Dale, I.L. / Shaw, J. / Phillips, C. / Hennessy, E.J. / Cheung, T. / Narvaez, A.J. |
External links | Acs Med. Chem. Lett. / PubMed:31531204 |
Methods | X-ray diffraction |
Resolution | 1.67 - 2.49 Å |
Structure data | PDB-6sd9: PDB-6sdc: PDB-6sdd: PDB-6sde: |
Chemicals | ChemComp-CL: ChemComp-88Z: ChemComp-HOH: ChemComp-353: ChemComp-GOL: ChemComp-V0L: |
Source |
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Keywords | TRANSFERASE / Kinase / inhibitor |